MCBO / Publications
Tuzlak S, Haschka MD, Mokina AM, Rülicke T, Cory S, Labi V, Villunger A
Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis
FEBS J. 2018 Mar 2. doi: 10.1111/febs.14426. [Epub ahead of print] PubMed PMID: 29498802.

Haschka M, Karbon G, Fava LL, Villunger A
Perturbing mitosis for anti-cancer therapy: is cell death the only answer?
EMBO Rep. 2018 Mar;19(3). pii: e45440. doi: 10.15252/embr.201745440. Epub 2018 Feb 19. Review. PubMe

Tan GC, Negro G, Pinggera A, Tizen Laim NMS, Mohamed Rose I, Ceral J, Ryska A, Chin LK, Kamaruddin NA, Mohd Mokhtar N, A Jamal AR, Sukor N, Solar M, Striessnig J, Brown MJ, Azizan EA

Hypertension (Dallas, Tex.: 1979), 5. Juni 2017

Ottina E, Peperzak V, Schoeler K, Carrington E, Sgonc R, Pellegrini M, Preston S, Herold MJ, Strasser A, Villunger A
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice
Nat Commun. 2017 Oct 18;8(1):1028. doi: 10.1038/s41467-017-01022-4. PubMed PMID: 29044097; PubMed Ce

Vogel G, Janecke A, Krainer I, Gutleben K, Witting B, Mitton S, Mansour S, Ballauff A, Roland J, Engevik A, Cutz E, Müller T, Goldenring J, Huber L, Hess M
Abnormal Rab11-Rab8-vesicles cluster in enterocytes of patients with Microvillus Inclusion Disease
Traffic. 2017 Apr 13. doi: 10.1111/tra.12486. [Epub ahead of print]

Rabachini T, Fernandez-Marrero Y, Montani M, Loforese G, Sladky V, He Z, Bachmann D, Wicki S, Villunger A, Stroka D, Kaufmann T
BOK promotes chemical-induced hepatocarcinogenesis in mice
Cell Death Differ. 2017 Dec 11. doi: 10.1038/s41418-017-0008-0. [Epub ahead of print] PubMed PMID: 2

Schenk R, Tuzlak S, Carrington E, Zhan Y, Heinzel S, Teh C, Gray D, Tai L, Lew A, Villunger A, Strasser A, Herold M
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Cell Death Differ. 2017 Mar;24(3):534-545. doi: 10.1038/cdd.2016.156. Epub 2017 Jan 13.

Schuler F, Weiss JG, Lindner SE, Lohmüller M, Herzog S, Spiegl SF, Menke P, Geley S, Labi V, Villunger A
Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis
Nat Commun. 2017 Nov 22;8(1):1697. doi: 10.1038/s41467-017-01850-4. PubMed PMID: 29167438; PubMed Ce

Janecke A, Xu R, Steichen-Gersdorf E, Waldegger S, Entenmann A, Giner T, Krainer I, Huber L, Hess M, Frishberg Y, Barash H, Tzur S, Schreyer-Shafir N, Sukenik-Halevy R, Zehavi T, Raas-Rothschild A, Mao C, Müller T
Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications
Hum Mutat. 2017 Apr;38(4):365-372. doi: 10.1002/humu.23192. Epub 2017 Mar 6.

Culig Z, Puhr M
Interleukin-6 and prostate cancer: Current developments and unsolved questions
Mol Cell Endocrinol. 2017 Mar 16. pii: S0303-7207(17)30181-8. doi: 10.1016/j.mce.2017.03.012. [Epub

Mastrolia V, Flucher S, Obermair G, Drach M, Hofer H, Renström E, Schwartz A, Striessnig J, Flucher B, Tuluc P
Loss of α2δ-1 Calcium Channel Subunit Function Increases the Susceptibility for Diabetes
Diabetes. 2017 Jan 23. pii: db151349. doi: 10.2337/db16-0336. [Epub ahead of print]

Ortner NJ, Bock G, Dougalis A, Kharitonova M, Duda J, Hess S, Tuluc P, Pomberger T, Stefanova N, Pitterl F, Ciossek T, Oberacher H, Draheim HJ, Kloppenburg P, Liss B, Striessnig J
Lower Affinity of Isradipine for L-Type Ca(2+) Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson’s Disease
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 37, Nr. 28 (12. Ju

Monteleone S, Lieb A, Pinggera A, Negro G, Fuchs JE, Hofer F, Striessnig J, Tuluc P, Liedl KR
Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains
Biophysical Journal 113, Nr. 7 (3. Oktober 2017): 1485–95

Pinggera, A, Mackenroth L, Rump A, Schallner J, Beleggia F, Wollnik B, Striessnig J
New Gain-of-Function Mutation Shows CACNA1D as Recurrently Mutated Gene in Autism Spectrum Disorders and Epilepsy
Human Molecular Genetics, 4. Mai 2017

Charoentong P, Finotello F, Angelova M, Mayer C, Efremova M, Rieder D, Hackl H, Trajanoski Z
Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
Cell Rep. 2017 Jan 3;18(1):248-262. doi: 10.1016/j.celrep.2016.12.019.

Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A
Signalling strength determines proapoptotic functions of STING
Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w. PubMed PMID: 28874664; PubMed Cent

Campiglio M, Flucher B
STAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triads
Sci Rep. 2017 Jan 23;7:41003. doi: 10.1038/srep41003.

Findeisen F, Campiglio M, Jo H, Abderemane-Ali F, Rumpf C, Pope L, Rossen N, Flucher B, DeGrado W, Minor DL Jr.
Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of CaV Function.
ACS Chem Neurosci. 2017 Mar 17. doi: 10.1021/acschemneuro.6b00454. [Epub ahead of print]

Tuzlak S, Schenk R, Vasanthakumar A, Preston S, Haschka M, Zotos D, Kallies A, Strasser A, Villunger A, Herold M
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection
Cell Death Differ. 2017 Mar;24(3):523-533. doi: 10.1038/cdd.2016.155. Epub 2017 Jan 13.

Lindner SE, Lohmüller M, Kotkamp B, Schuler F, Knust Z, Villunger A, Herzog S
The miR-15 family reinforces the transition from proliferation to differentiation in pre-B cells
EMBO Rep. 2017 Sep;18(9):1604-1617. doi: 10.15252/embr.201643735. Epub 2017 Jul 13. PubMed PMID: 287

Fava L, Schuler F, Sladky V, Haschka M, Soratroi C, Eiterer L, Demetz E, Weiss G, Geley S, Nigg E, Villunger A
The PIDDosome activates p53 in response to supernumerary centrosomes
Genes Dev. 2017 Jan 1;31(1):34-45. doi: 10.1101/gad.289728.116.

Pichler R, Fritz J, Heidegger I, Steiner E, Culig Z, Klocker H, Fuchs D
The predictive and prognostic role of serum neopterin and tryptophan breakdown in prostate cancer.
Cancer Sci. 2017 Jan 20. doi: 10.1111/cas.13171. [Epub ahead of print]

Sladky V, Schuler F, Fava LL, Villunger A
The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance
J Cell Sci. 2017 Nov 15;130(22):3779-3787. doi: 10.1242/jcs.203448. Review. PubMed PMID: 29142064.