Lieb Andreas,

University / Clinic:
Institute: Institute of Pharmacy
 
Research Area:

Email: andreas.lieb@uibk.ac.at
Web: www.uibk.ac.at/pharmazie/pharmakologie/


Research Topic:


Selected publications:
 
  Monteleone S, Lieb A, Pinggera A, Negro G, Fuchs JE, Hofer F, Striessnig J, Tuluc P, Liedl KR
Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains
Biophysical Journal 113, Nr. 7 (3. Oktober 2017): 1485–95

  Pinggera A, Lieb A, Benedetti B, Lampert M, Monteleone S, Liedl K, Tuluc P, Striessnig J
CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.
Biol Psychiatry. 2015 May 1;77(9):816-22.

  Kaur G, Pinggera A, Ortner N, Lieb A, Sinnegger-Brauns M, Yarov-Yarovoy V, Obermair G, Flucher B, Striessnig J
A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-Gated Cav1.2 Calcium Channel Function.
J Biol Chem. 2015 Aug 21;290(34):21086-100.

  Lieb A, Ortner N, Striessnig J
C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1.3 L-type Ca(2+) channels.
Biophys J. 2014 Apr 1;106(7):1467-75.

  Lieb A, Scharinger A, Sartori S, Sinnegger-Brauns M, Striessnig J
Structural determinants of CaV1.3 L-type calcium channel gating.
Channels (Austin). 2012 May-Jun;6(3):197-205

  Baig S, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns M, Brandt N, Engel J, Mangoni M, Farooq M, Khan H, Nürnberg P, Striessnig J, Bolz H
Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness.
Nat Neurosci. 2011 Jan;14(1):77-84.