Pinggera Alexandra,

University / Clinic: University of Innsbruck
Institute: Institute of pharmacy, Department of pharmacology and toxicology
Research Area: Modulation of voltage gated calcium channels due to protein interactions and mutations


  Funded by: FWF

Research Topic:
мери кей
mary kay

Selected publications:
  Monteleone S, Lieb A, Pinggera A, Negro G, Fuchs JE, Hofer F, Striessnig J, Tuluc P, Liedl KR
Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains
Biophysical Journal 113, Nr. 7 (3. Oktober 2017): 1485–95

  Tan GC, Negro G, Pinggera A, Tizen Laim NMS, Mohamed Rose I, Ceral J, Ryska A, Chin LK, Kamaruddin NA, Mohd Mokhtar N, A Jamal AR, Sukor N, Solar M, Striessnig J, Brown MJ, Azizan EA

Hypertension (Dallas, Tex.: 1979), 5. Juni 2017

  Pinggera A, Striessnig J
Cav 1.3 (CACNA1D) L-type Ca2+ channel dysfunction in CNS disorders.
J Physiol. 2016 Feb 4. doi: 10.1113/JP270672.

  Stanika R, Campiglio M, Pinggera A, Lee A, Striessnig J, Flucher B, Obermair G
Splice variants of the CaV1.3 L-type calcium channel regulate dendritic spine morphology
Sci Rep. 2016 Oct 6;6:34528. doi: 10.1038/srep34528

  Pinggera A, Lieb A, Benedetti B, Lampert M, Monteleone S, Liedl K, Tuluc P, Striessnig J
CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.
Biol Psychiatry. 2015 May 1;77(9):816-22.

  Kaur G, Pinggera A, Ortner N, Lieb A, Sinnegger-Brauns M, Yarov-Yarovoy V, Obermair G, Flucher B, Striessnig J
A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-Gated Cav1.2 Calcium Channel Function.
J Biol Chem. 2015 Aug 21;290(34):21086-100.

  Striessnig J, Ortner N, Pinggera A
Pharmacology of L-type calcium channels: novel drugs for old targets?
Curr Mol Pharmacol. 2015;8(2):110-22.

  Striessnig J, Pinggera A, Kaur G, Bock G, Tuluc P
L-type Ca2+ channels in heart and brain.
Wiley Interdiscip Rev Membr Transp Signal. 2014 Mar 1;3(2):15-38.