Klepsch-Pedit Victoria, MSc

University / Clinic: Medical University Innsbruck
Institute: Deptartment for Medical Genetics, Clinical and Molecular Pharmacology
Research Area: tumor immunology, nuclear receptors

Email: victoria.pedit@i-med.ac.at

  Funded by: FWF

Research Topic:

Selected publications:
  Pfeifhofer-Obermair C, Albrecht-Schgör K, Peer S, Nairz M, Siegmund K, Klepsch-Pedit V, Haschka D, Thuille N, Hermann-Kleiter N, Gruber T, Weiss G, Baier G
Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice.
Cell Commun Signal. 2016 Jul 28;14(1):14

  Siegmund K, Klepsch-Pedit V, Hermann-Kleiter N, Baier G
Proof of Principle for a T Lymphocyte Intrinsic Function of Coronin 1A.
J Biol Chem. 2016 Oct 14;291(42):22086-22092. Epub 2016 Aug 26.

  Klepsch-Pedit V, Hermann-Kleiter N, Baier G
Beyond CTLA-4 and PD-1: Orphan nuclear receptor NR2F6 as T cell signaling switch and emerging target in cancer immunotherapy.
Immunol Lett. 2016 Oct;178:31-6. doi: 10.1016/j.imlet.2016.03.007. Epub 2016 Mar 15.

  Hermann-Kleiter N, Klepsch-Pedit V, Wallner S, Siegmund K, Klepsch S, Tuzlak S, Villunger A, Kaminski S, Pfeifhofer-Obermair C, Gruber T, Wolf D, Baier G
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell Rep. 2015 Sep 29;12(12):2072-85.

  Schuler F, Baumgartner F, Klepsch-Pedit V, Chamson M, Müller-Holzner E, Watson C, Oh S, Hennighausen L, Tymoszuk P, Doppler W, Villunger A
The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.
Cell Death Differ. 2015 Jun 5. doi: 10.1038/cdd.2015.61. [Epub ahead of print]

  Baumgartner F, Wöss C, Klepsch-Pedit V, Tzankov A, Labi V, Villunger A
Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf.
Oncogene. 2013 Jan 31;32(5):621-30