Tuzlak Selma,

University / Clinic:
Research Area:

Email: Selma.Tuzlak@i-med.ac.at

Research Topic:

Selected publications:
  Tuzlak S, Haschka MD, Mokina AM, Rülicke T, Cory S, Labi V, Villunger A
Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis
FEBS J. 2018 Mar 2. doi: 10.1111/febs.14426. [Epub ahead of print] PubMed PMID: 29498802.

  Tuzlak S, Schenk R, Vasanthakumar A, Preston S, Haschka M, Zotos D, Kallies A, Strasser A, Villunger A, Herold M
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection
Cell Death Differ. 2017 Mar;24(3):523-533. doi: 10.1038/cdd.2016.155. Epub 2017 Jan 13.

  Schenk R, Tuzlak S, Carrington E, Zhan Y, Heinzel S, Teh C, Gray D, Tai L, Lew A, Villunger A, Strasser A, Herold M
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Cell Death Differ. 2017 Mar;24(3):534-545. doi: 10.1038/cdd.2016.156. Epub 2017 Jan 13.

  Sochalska M, Ottina E, Tuzlak S, Herzog S, Herold M, Villunger A
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival.
Cell Death Differ. 2016 Apr;23(4):628-39. doi: 10.1038/cdd.2015.130. PubMed PMID: 26450454; PubMed C

  Tuzlak S, Kaufmann T, Villunger A
Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis.
Genes Dev. 2016 Oct 1;30(19):2133-2151. Review. PubMed PMID: 27798841; PubMed Central PMCID: PMC5088

  Amort M, Nachbauer B, Tuzlak S, Kieser A, Schepers A, Villunger A, Polacek N
Expression of the vault RNA protects cells from undergoing apoptosis.
Nat Commun. 2015 May 8;6:7030.

  Wöss C, Tuzlak S, Labi V, Drach M, Bertele D, Schneider P, Villunger A
Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice.
Cell Death Differ. 2015.

  Sochalska M, Tuzlak S, Egle A, Villunger A
Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.
FEBS J. 2015 Mar;282(5):834-49.

  Hermann-Kleiter N, Klepsch-Pedit V, Wallner S, Siegmund K, Klepsch S, Tuzlak S, Villunger A, Kaminski S, Pfeifhofer-Obermair C, Gruber T, Wolf D, Baier G
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell Rep. 2015 Sep 29;12(12):2072-85.

  Labi V, Wöss C, Tuzlak S, Erlacher M, Bouillet P, Strasser A, Tzankov A, Villunger A
Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.
Blood. 2014 Apr 24;123(17):2652-62